"Un barril sin fondo" / "A bottomless barrel" / "Un tonneau sans fond" / "Um barril sem fundo

Belcebú es la historia de un niño con las marcas de la violencia que se perpetúa transgeneracionalmente. Su nombre remite a marcas identitarias confusas y ambivalentes. Ser demonio o exorcista. Ser exceso o restricción. Ser de la abuela o de mamá. Ser un niño o (no ser) un robot. Ser un peso o un sostén. Es también la historia del juego elaborativo en pandemia y con modalidad virtual. Y,por último,es la historia del alcance del analista frente a un contexto de mucha vulnerabilidad AU

Belcebu is the story of a boy with the singsof violence that are perpetuated transgenerationally. His name refers to confusing and ambivalent identity marks. To be a demon or an exorcist. To be excess or restraint. To be from grandma or from mom. To be a child or (not to be) a robot. To be a burden or a support.It is also the story of elaborative play during a pandemic and with virtual modality.And finally, it is the story of the analyst's reach in the face of a context of great vulnerability AU

Belzébuth est l'histoire d'un enfant marqué par la violence qui se perpétue de manière transgénération nelle. Son nom fait référence à des marques d'identitéconfuses et ambivalentes. Être un démon ou un exorciste. Être un excès ou une restriction. Être de grand-mère ou de maman. Être un enfant ou (ne pas être) un robot. Être un poids ou un support.C'est aussi l'histoire du jeu élaboratif dans une pandémie et avec une modalité virtuelle.Et enfin, c'est l'histoire de la portée de l'analyste dans un contexte de grande vulnérabilité AU

Belzebu é ahistória de uma criança com as marcas da violência que se perpetua transgeracionalmente. Seu nome remete a marcas identitárias confusas e ambivalentes. Ser um demônio ou exorcista. Ser excesso ou restrição. Seja da avó ou da mãe. Ser criança ou (não ser) robô. Sendo um peso ou um suporte.É também a história do jogo elaborativo em plena pandemia e com modalidade virtual.E, finalmente, é a história do alcance do analista em um contexto de grande vulnerabilidade AU

A psicopatia e o criminoso nato: a modernização do positivismo criminológico / Psychopathy and the born criminal: the modernization of criminological positivism / Psicopatía y el criminal nato: la modernización del positivismo criminológico

O conceito de psicopatia é habitualmente associado a uma psicopatologia caracterizada pela falta de empatia, manipulação, agressividade, impulsividade, egocentrismo, crueldade e criminalidade. Já amplamente aceito pela comunidade científica, o conceito costuma ser utilizado em contextos jurídico-penais na validação de seu funcionamento punitivo. Dentre as concepções que alicerçaram o surgimento histórico desse conceito, destaca-se o papel do criminoso nato de Lombroso. Nesse sentido, este estudo buscou evidenciar como o conceito contemporâneo de psicopatia se firma enquanto modernização das concepções lombrosianas acerca do criminoso nato. Para isso, nos apoiamos na psicopatolologia para realizar um estudo comparativo entre as produções de Lombroso e as pesquisas contemporâneas acerca da psicopatia. Dentre as principais similaridades, destacamos a ênfase atribuída à suposta natureza criminal, etiologicamente decorrente de sua configuração orgânica. No mais, tais concepções também se assemelham no destaque de um déficit afetivo e moral, assim como na descrição da tendência a ser canhoto, egoísta, mentiroso, resistente à dor, narcisista, impulsivo, promíscuo, cruel, maléfico e inapto ao trabalho. Assim como fez Lombroso, as pesquisas acerca da psicopatia costumam ser realizadas com sujeitos já previamente criminalizados; condicionando uma seletividade étnico-racial e de classe. Descritos como sujeitos perigosos, incuráveis e intratáveis, ambas as concepções promovem a defesa do acirramento da punição jurídico-penal. Concluímos que a criminalidade nata de Lombroso continua a ser expressa no conceito de psicopatia, visto que as funções jurídico-penais e socioeconômicas de sua definição exercem o mesmo papel na legitimação científica da violência de Estado, encarceramento em massa e racismo estrutural.(AU)

Psychopathy is usually associated with a psychopathology characterized by a lack of empathy, manipulation, aggressiveness, impulsivity, egocentrism, cruelty, and criminality. Widely accepted by the scientific community, this concept is often used in legal and criminal contexts to validate its punitive functioning. Among the conceptions that underpinned the historical emergence of psychopathy, Lombroso's born criminal stands out. Hence, this study analyzes how the contemporary concept of psychopathy updates Lombrosian conceptions about the born criminal. To do so, we rely on psychopathology to conduct a comparative study between Lombroso's work and contemporary research on psychopathy. Among the main similarities, we highlight the emphasis given to the supposed criminal nature, etiologically arising from its organic configuration. Moreover, such conceptions emphasize an affective and moral deficit, and describe a tendency toward left-handedness, selfishness, lying, pain-resistance, narcissism, impulsivity, promiscuousness, cruelty, maliciousness and unfitness for work. As did Lombroso, research on psychopathy is usually conducted with individuals who have already been criminalized, conditioning an ethnic-racial and class selectivity. By describing these subjects as dangerous, incurable and intractable, both conceptions advocate for increased legal and penal punishment. In conclusion, Lombroso's natural criminality continues to underpin the concept of psychopathy, since its legal-criminal and socioeconomic functions play the same role in scientifically legitimizing state violence, mass incarceration, and structural racism.(AU)

La psicopatía es un concepto generalmente asociado a una psicopatología que se caracteriza por la falta de empatía, la manipulación, agresividad, impulsividad, egocentrismo, crueldad y criminalidad. Ya ampliamente aceptado por la comunidad científica, este concepto se utiliza a menudo en contextos legales para validar su funcionamiento punitivo. Entre los conceptos que fundamentaron el surgimiento histórico de este concepto, destaca el papel del criminal nato de Lombroso. En este contexto, este estudio buscó mostrar cómo el concepto contemporáneo de psicopatía se establece como la modernización de las concepciones lombrosianas sobre el criminal nato. Para eso, se utiliza la psicopatología para realizar un estudio comparativo entre las producciones de Lombroso y la investigación contemporánea sobre psicopatía. Entre las principales similitudes, destaca el énfasis atribuido a su supuesta naturaleza criminal, resultado etiológico de su configuración orgánica. Además, estas concepciones también son similares al resaltar un déficit afectivo y moral, así como al describir la tendencia a ser zurdo, egoísta, mentiroso, resistente al dolor, narcisista, impulsivo, promiscuo, cruel, malévolo e inadecuado para el trabajo. Como hizo Lombroso, los estudios sobre psicopatía se suelen realizar con sujetos que ya han sido criminalizados; condicionando una selectividad étnica, racial y de clase. Calificados como sujetos peligrosos, incurables e intratables, ambas concepciones promueven la defensa del aumento de la pena legal. Se concluye que la criminalidad nata de Lombroso continúa expresándose en el concepto de psicopatía, ya que las funciones penales y socioeconómicas de su definición juegan el mismo papel en la legitimación científica de la violencia estatal, encarcelamiento masivo y racismo estructural.(AU)

Violência por parceiro íntimo entre homens que se relacionam com homens / Intimate partner violence among men who relate with men / Violencia de pareja íntima entre hombres que tienen relaciones con hombres

A violência por parceiro íntimo (VPI) consiste em atos que ameacem causar ou efetivamente causem danos em um parceiro dentro de uma relação afetivo-sexual, independente da configuração ou tempo do relacionamento ou de haver coabitação ou não entre as partes. Nas relações homossexuais, a VPI é invisibilizada de diversas maneiras, mesmo sendo reconhecida como uma grave violação de direitos humanos. O estudo objetivou compreender os significados da VPI para um grupo de homens que se relacionam com homens (HRH). Participaram da pesquisa oito HRH, selecionados através da técnica "bola de neve", utilizada devido à sensibilidade do tema, considerando os estigmas de ser HRH. Os dados foram obtidos através de entrevista semiestruturada e foram analisados pela Análise Temática. Como resultados, foram construídas seis categorias: 1º) O armário; 2º) Homofobia 3º) Racismo, poder e vulnerabilidade a VPI; 4º) Sexualidade; 5º) Infidelidade; 6º) HIV, que discutem a interseccionalidade de diversas formas de opressão na produção de VPI entre HRH. Conclui-se que a VPI vivenciada por esse grupo é influenciada por diversos fatores que envolvem a interseccionalidade de vários marcadores sociais, como os estereótipos de masculinidade em relação a hipersexualização e infidelidade, a homofobia como fator direto do estresse minoritário, o racismo que hierarquiza os corpos e invisibiliza o afeto de homens negros, e o estigma de HIV no imaginário social.(AU)

Intimate partner violence (IPV) consists of acts that threaten to harm or actually harm to a partner within an affective-sexual relationship, regardless of the configuration or duration of the relationship or whether or not there is cohabitation between the parties. In homosexual relationships, IPV is made invisible in several ways, even though it is recognized as a serious violation of human rights. The study aimed to understand the meanings of IPV for a group of men in same sex relationships (MSSR). Eight MSSR participated in the research, selected by snowball sampling, used due to the topic's sensitivity, considering the stigmas involved in being MSSR. Data were constructed via semi-structured interviews and analyzed using Thematic Analysis. As a result, six categories were constructed: 1) The closet persons; 2) Homophobia; 3) Racism, power, and vulnerability to IPV; 4) Sexuality; 5) Infidelity; 6) HIV, which discuss the intersectionality of various forms of oppression in the production of IPV among MSSR. Thus, the IPV experienced by this group is influenced by several factors that involve the intersectionality between different social markers, such as stereotypes of masculinity in relation to hypersexualization and infidelity, homophobia as a direct factor of minority stress, the racism that hierarchizes bodies and makes the affection of Black men and the stigma of HIV invisible in the social imaginary.(AU)

La violencia de pareja (VP) consiste en actos que amenazan con causar o de hecho causan daño a una pareja dentro de una relación afectivo-sexual, independientemente de la configuración o duración de la relación o de si existe o no cohabitación entre las partes. En las relaciones homosexuales, la VP se invisibiliza de varias formas, a pesar de que se reconoce como una grave violación de los derechos humanos. Este estudio tuvo como objetivo comprender los significados de VP para un grupo de hombres que se relacionan con hombres (HRH). Ocho HRH participaron de la investigación, seleccionados mediante la técnica de "bola de nieve", utilizada debido a la sensibilidad del tema, considerando los estigmas de ser HRH. Los datos se construyeron mediante entrevistas semiestructuradas y se sometieron a análisis temático. Como resultado se construyeron seis categorías: 1.ª) El armario; 2.º) Homofobia; 3.º) Racismo, poder y vulnerabilidad a la VP; 4.º) Sexualidad; 5.º) Infidelidad; 6.ª) HIV; que discuten la interseccionalidad de diferentes formas de opresión en la producción de VP entre HRH. Se concluye que la VP vivida por este grupo está influida por varios factores que involucran la interseccionalidad entre distintos marcadores sociales, como los estereotipos de masculinidad en relación con la hipersexualización y la infidelidad, la homofobia como factor directo de estrés minoritario, el racismo que jerarquiza cuerpos e invisibiliza en el imaginario social el afecto de los hombres negros y el estigma del HIV en el imaginario social.(AU)

Atendimento psicossocial à mulher que comete ofensa sexual / Psychosocial attention for women that commit sexual offenses / Atención psicosocial para mujeres que cometen delitos sexuales

Objetivamos apresentar uma proposta de atendimento psicossocial grupal oferecida para mulheres adultas que cometeram ofensa sexual, cuidadoras e mães. A experiência está sendo desenvolvida no Distrito Federal, Brasil, com pessoas do gênero feminino provenientes de encaminhamento judicial. Carece que os profissionais das áreas da justiça, saúde, serviço social e psicologia avancem no estudo e na compreensão desta temática, de modo a pensarem a atuação e o apoio terapêutico a essas mulheres. O modo de atendimento é focal e breve, com ênfase na criação de um ambiente lúdico como facilitador das interações grupais e da discussão sobre os temas: identidade; confiança nas relações afetivas e sociais; vivência pessoal com violência física e sexual; configuração de gênero; e expressão da sexualidade e futuro. A abordagem individual também se baseia no enfoque dos temas mencionados. O oferecimento de ajuda à mulher cuidadora ou à mãe tem participação ativa na interrupção do circuito abusivo sexual, pois essa violência é extremamente ocultada, ocasionando uma prolongada vulnerabilidade para as vítimas. Ressalta-se o valor do texto indicando a descrição de ação voltada para uma população permanentemente não estudada e evitada em seu reconhecimento. Os limites desta proposta encontram-se na falta de outras iniciativas que possibilitem uma discussão sobre essa experiência.(AU)

We aim to present a proposal of a group psychosocial intervention offered for adult female sexual offenders, caregivers, and mothers. The intervention is being developed at Federal District, Brazil, with female people coming from judicial referrals. Professionals in the areas of justice, health, social work, and psychology need to advance in the study and understanding this theme to think about action and therapeutic support for these women. The intervention is a focal and brief approach, with emphasis on the creation of a ludic environment as a facilitator of group interactions and discussion about the themes: identity; trust in affective and social relationships; personal experience with physical and sexual violence; gender configuration; and sexuality expression and future. The individual approach is also based on focusing on these themes. The offering of help to the female caregiver or the mother has an active participation in the interruption of the sexual offense circuit, since this violence is extremely hidden, bringing a prolonged condition of vulnerability to the victims. The value of this text is highlighted indicating the description of an action directed to a population that is permanently not studied and whose recognition is avoided. The limits of this proposal are found in the absence of other initiatives that would allow a discussion about this experience.(AU)

Este texto presenta una propuesta de atención psicosocial grupal destinada a mujeres adultas que han cometido delito sexual, a cuidadoras y madres. La intervención se está desarrollando en el Distrito Federal (Brasil), con personas del género femenino provenientes de remisiones judiciales. Es necesario que los profesionales de las áreas de justicia, salud, trabajo social y psicología avancen en el estudio y comprensión de esta temática para pensar en el desempeño y apoyo terapéutico de estas mujeres. El servicio es enfocado y breve, con énfasis en la creación de un ambiente lúdico como facilitador de interacciones grupales y discusión sobre los temas: identidad; confianza en las relaciones afectivas y sociales; experiencia personal con violencia física y sexual; configuración de género; y expresión de la sexualidad y el futuro. El enfoque individual también se centra en estos temas. La oferta de ayuda a la mujer cuidadora o a la madre es importante para la interrupción del circuito de abuso sexual, ya que esta violencia es extremadamente oculta y provoca una vulnerabilidad prolongada a las víctimas. Se destaca el valor del texto con la descripción de la acción dirigida a una población que no es objeto de estudios ni reconocida. Los límites de esta propuesta se encuentran en la ausencia de otras iniciativas que permitan un debate sobre esta experiencia.(AU)

A utilização da imitação facial em tarefas de reconhecimento de expressões emocionais / The use of facial mimicry in emotional expressions recognition tasks / El uso de la imitación facial en tareas de reconocimiento de expresiones emocionales

A imitação facial é um comportamento involuntário capaz de facilitar a transmissão de informações não verbais relevantes em diferentes contextos sociais. Este estudo teve por objetivo analisar a capacidade de reconhecimento de expressões emocionais enquanto o observador tensiona a própria face ou imita a face-alvo. A hipótese utilizada foi a de que indivíduos que tensionam a própria face terão menor probabilidade de acertos na execução das tarefas de reconhecimento de expressões emocionais e aqueles que imitam a expressão terão uma maior probabilidade de acertos na execução das mesmas tarefas. A amostra foi composta por 30 participantes, divididos em dois grupos experimentais: o Grupo Imitação (GI) e o Grupo Ruído (GR), ambos com 18 participantes do sexo feminino e 12 do sexo masculino. O experimento consistiu em apresentar fotos de atores expressando facialmente uma emoção básica por 10 segundos. Neste período, os participantes deveriam, então, observar ou intervir facialmente, imitando ou tensionando a própria face (de acordo com o grupo alocado, Imitação ou Ruído). Após os 10 segundos executando a instrução (observar, imitar ou interferir), o participante deveria responder - entre as opções alegria, tristeza, nojo, raiva, surpresa e medo - a emoção correspondente à imagem. Os resultados apresentaram diferenças significativas quando comparadas as tarefas de tensionar ou imitar a face-alvo, sugerindo que a alteração da própria face do observador pode influenciar durante o desempenho de uma tarefa de reconhecimento de emoções em faces.(AU)

Facial mimicry is an involuntary behavior capable of facilitating the transmission of relevant non-verbal information in different social contexts. The present study aimed to analyze the ability to recognize emotional expressions while the observer tenses their own face or imitates the target face. The hypothesis used was that individuals who tension their own face or imitate the expression of facial emotion have less or greater probability of success in performing tasks to recognize emotional expressions on faces, respectively. The sample consisted of 30 participants, divided into two experimental groups: the Imitation Group - GI (18 female participants and 12 male participants) and the Noise Group - GR (18 female participants and 12 male participants). The experiment consisted of presenting pictures of actors facially expressing a basic emotion for 10 seconds; the participants should then observe or intervene facially, imitating or tensing their own face (according to the allocated group, Imitation or Noise). After 10 seconds of executing the instruction (observing, imitating or interfering), the participant should respond - among the options joy, sadness, disgust, anger, surprise and fear - the emotion corresponding to the image. The results showed significant differences when comparing the tasks of tensioning or imitating the target face, suggesting that the alteration of the observer's own face may influence during the performance of a facial emotion recognition task.(AU)

La imitación facial es un comportamiento involuntario capaz de facilitar la transmisión de información no verbal relevante en diferentes contextos sociales. Esto estudio tuvo como objetivo analizar la capacidad de reconocer expresiones emocionales mientras el observador tensa su propio rostro o imita el rostro objetivo. Se utilizó la hipótesis de que los individuos que tensan su propio rostro tendrán menor probabilidad de éxito en la realización de tareas de reconocimiento de expresiones emocionales y los individuos que imitan la expresión tendrán una mayor probabilidad de éxito en la realización de las mismas tareas. La muestra estuvo formada por 30 participantes divididos en dos grupos experimentales: el Grupo de Imitación - GI (18 mujeres y 12 hombres) y el Grupo de Ruido - GR (18 mujeres y 12 hombres). El experimento consistió en presentar imágenes de actores expresando facialmente una emoción básica durante 10 segundos; los participantes deberían entonces observar o intervenir facialmente, imitando o tensando su propio rostro (según el grupo asignado, Imitación o Ruido). Después de 10 segundos de ejecutar la instrucción (observar, imitar o interferir), el participante debería responder - entre las opciones de alegría, tristeza, asco, ira, sorpresa y miedo - la emoción correspondiente a la imagen. Los resultados mostraron diferencias significativas al comparar las tareas de tensar o imitar el rostro objetivo, sugiriendo que la alteración del propio rostro del observador puede influir durante la realización de una tarea de reconocimiento de emociones en rostros.(AU)

Impacto de la implementación de inicio temprano de terapia antirretroviral en nuevos diagnósticos de VIH: estudio de casos y controles / Impact of the implementation of early initiation of antiretroviral therapy in new HIV diagnoses: case-control study

Antecedentes: En Honduras aún se prioriza asegurar la aceptación del diagnóstico de Virus de Inmunodeficiencia Humana (VIH) y la adherencia al tratamiento del Terapia Anti Retroviral (TAR), provocando retraso en su inicio, consecuencias negativas y alto riesgo de muerte. Objetivo: Evaluar el impacto del inicio temprano de TAR en pacientes con nuevos diagnósti- cos de VIH en el Hospital Nacional Mario Catarino Rivas (HNMCR). Pacientes y Métodos: Investigación analítica, observacional de casos y controles. Muestra: 62 casos que iniciaron TAR temprano, de enero a agosto del 2019 y 62 controles que iniciaron TAR en el 2018, fuera de la estrategia de inicios tempranos. Se tomaron datos de expedientes clínicos y se vacío la información en instrumento tipo cuestionario. Resultados: Se encontró más rápida vinculación al servicio y más inicios tempranos de TAR en el grupo casos (OR 19.6, IC 95% 7.2-53.0, p=0.000), una mayor captación en etapa temprana A1 (OR 3.45, IC 95% 1.36-8.59, p=0.006), un menor cambio de estadio clínico (OR 2.35, IC 95% 0.92-5.98, p= 0.070), mayor cumplimiento de evaluación psicológica (OR 8.15, IC 95% 3.42-19.4, p=0.000), menor riesgo de infecciones oportunistas (OR 3.01, IC 95% 1.34-6.74, p=0.006), menor riesgo de hospita- lización (OR 1.33, IC 95% 0.46-3.84, p=0.596), mayor tamizaje de IO (p=0.000). Conclusión /Recomendación: El inicio del TAR en los primeros 7 días posterior al diagnóstico aporta beneficios clínicos y profilácticos, mejorando la calidad de vida y disminuyendo la transmisibilidad del virus. Se recomienda protocolizar los inicios tempranos como estrategia de atención a los nuevos diagnósticos de VIH...(AU)

Técnicas para Manejo da Emoção de Raiva: Uma Revisão Sistemática / Anger Management Techniques: A Systematic Review / Técnicas para el Manejo de la Emoción de Rabia: Una Revisión Sistemática

Introdução: Dentre as inúmeras possibilidades que um indivíduo possui de experienciar e expressar a raiva ou a ira, não é raro que o sentimento fuja do controle e termine em hostilidade e agressões, podendo gerar consequências importantes na vida de uma pessoa e de outros ao seu redor. Diante disso, torna-se fundamental a aplicação de técnicas comprovadamente eficazes, objetivando uma maior qualidade de vida ao indivíduo e às pessoas que com ele convivem. Objetivos: Identificar as principais técnicas no manejo da raiva em adultos. Método: Revisão sistemática de artigos científicos de estudos clínicos. Resultados: Nove estudos clínicos randomizados com utilização de técnicas psicológicas para o manejo da ira foram utilizados na análise. A Terapia Cognitivo-Comportamental mostrou-se predominante nas intervenções analisadas e provou-se eficaz para o controle da ira. Conclusão: Técnicas cognitivo-comportamentais, em especial a psicoeducação e a reestruturação cognitiva, são as ferramentas mais frequentemente usadas para o manejo da raiva em distintos grupos clínicos de pacientes, com resultados positivos na regulação emocional.

Introduction: Among the innumerable possibilities that an individual has to experience and express anger, it is not rare that the feeling gets out of control and ends up in hostility and aggressions, which can lead to important consequences in a person's life and others around. Given this, it is fundamental to apply techniques which are proven effective, aiming at a higher quality of life for the individual and for people who live with them. Objectives: To identify the main techniques for anger management in adults. Method: Systematic review of scientific papers from clinical trials. Results: Nine randomized clinical trials using psychological techniques for anger management were used in the present analysis. Cognitive-Behavioral Therapy was shown to be predominant in the analyzed interventions and proved to be effective in controlling anger. Conclusion: Cognitive Behavioral Therapy, especially psychoeducation and cognitive restructuring, are the most frequently used techniques for anger management in several clinical groups of patients, with positive results in emotional regulation.

Introducción: Entre las innumerables posibilidades que un individuo tiene de experimentar y expresar rabia o ira, no es raro que el sentimiento huya del control y termine en hostilidad y agresiones, pudiendo generar consecuencias graves en la vida de una persona y de otros a su alrededor. Por eso, es fundamental la aplicación de técnicas comprobadamente eficaces, objetivando una mayor calidad de vida al individuo y a las personas que con él conviven. Objetivos: Identificar las principales técnicas para el manejo de la rabia en adultos. Método: Revisión Sistemática de artículos científicos de estudios clínicos. Resultados: Se utilizaron nueve estudios clínicos aleatorizados con utilización de técnicas psicológicas para el manejo de la ira en el análisis. Terapia Cognitivo-Conductual demostró ser predominante en las intervenciones analizadas y eficaz para controlar la ira. Conclusión: La Terapia Cognitivo-Conductual, en especial la psicoeducación y la reestructuración cognitiva, son las técnicas más frecuentemente usadas para el manejo de la rabia en varios grupos clínicos de pacientes, con resultados positivos en regulación emocional.

Neuroinflammation, body temperature and behavioural changes in CD1 male mice undergoing acute restraint stress: An exploratory study.

BACKGROUND: Animal models used to study pathologies requiring rehabilitation therapy, such as cardiovascular and neurologic disorders or oncologic disease, must be as refined and translationally relevant as possible. Sometimes, however, experimental procedures such as those involving restraint may generate undesired effects which may act as a source of bias. However, the extent to which potentially confounding effects derive from such routine procedures is currently unknown. Our study was therefore aimed at exploring possible undesirable effects of acute restraint stress, whereby animals were exposed to a brightly lit enclosed chamber (R&L) similar to those that are commonly used for substance injection. We hypothesised that this would induce a range of unwanted physiological alterations [such as neuroinflammatory response and changes in body weight and in brown adipose tissue (BAT)] and behavioural modification, and that these might be mitigated via the use of non-aversive handling methods: Tunnel Handling (NAH-T) and Mechanoceptive Handling (NAH-M)) as compared to standard Tail Handling (TH). METHODS: Two indicators of physiological alterations and three potentially stress sensitive behavioural parameters were assessed. Physiological alterations were recorded via body weight changes and assessing the temperature of Brown Adipose Tissue (BAT) using infra-red thermography (IRT), and at the end of the experiment we determined the concentration of cytokines CXCL12 and CCL2 in bone marrow (BM) and activated microglia in the brain. Nest complexity scoring, automated home-cage behaviour analysis (HCS) and Elevated Plus Maze testing (EPM) were used to detect any behavioural alterations. Recordings were made before and after a 15-minute period of R&L in groups of mice handled via TH, NAH-T or NAH-M. RESULTS: BAT temperature significantly decreased in all handling groups following R&L regardless of handling method. There was a difference, at the limit of significance (p = 0.06), in CXCL12 BM content among groups. CXCL12 content in BM of NAH-T animals was similar to that found in Sentinels, the less stressed group of animals. After R&L, mice undergoing NAH-T and NAH-M showed improved body-weight maintenance compared to those exposed to TH. Mice handled via NAH-M spent a significantly longer time on the open arms of the EPM. The HCS results showed that in all mice, regardless of handling method, R&L resulted in a significant reduction in walking and rearing, but not in total distance travelled. All mice also groomed more. No difference among the groups was found in Nest Score, in CCL2 BM content or in brain activated microglia. CONCLUSIONS: Stress induced by a common restraint procedure caused metabolic and behavioural changes that might increase the risk of unexpected bias. In particular, the significant decrease in BAT temperature could affect the important metabolic pathways controlled by this tissue. R&L lowered the normal frequency of walking and rearing, increased grooming and probably carried a risk of low-grade neuro-inflammation. Some of the observed alterations can be mitigated by Non-aversive handlings.

Urocanic acid enhances memory consolidation and reconsolidation in novel object recognition task.

Urocanic acid (UCA) is an endogenous small molecule that is elevated in skin, blood and brain after sunlight exposure, mainly playing roles in the periphery systems. Few studies have investigated the role of UCA in the central nervous system. In particular, its role in memory consolidation and reconsolidation is still unclear. In the present study, we investigated the effect of intraperitoneal injection of UCA on memory consolidation and reconsolidation in a novel object recognition memory (ORM) task. In the consolidation version of the ORM task, the protocol involved three phases: habituation, sampling and test. UCA injection immediately after the sampling period enhanced ORM memory performance; UCA injection 6 h after sampling did not affect ORM memory performance. In the reconsolidation version of the ORM task, the protocol involved three phases: sampling, reactivation and test. UCA injection immediately after reactivation enhanced ORM memory performance; UCA injection 6 h after reactivation did not affect ORM memory performance; UCA injection 24 h after sampling without reactivation did not affect ORM memory performance. This UCA-enhanced memory performance was not due to its effects on nonspecific responses such as locomotor activity and exploratory behavior. The results suggest that UCA injection enhances consolidation and reconsolidation of an ORM task, which further extends previous research on UCA effects on learning and memory.

Afrontamiento de los efectos psicológicos de la pandemia por COVID-19

La dependencia emocional: un problema de la psicología y otras ciencias humanísticas / Emotional dependence: a problem in psychology and other humanistic sciences

RESUMEN Introducción: se consideran las ideas de L.S. Vygotsky (1896-1934) teórico del enfoque histórico-cultural con su propuesta para elaborar una teoría y práctica psicológica materialista-dialéctica. Objetivo: valorar la dependencia emocional con sus causas y factores asociados a partir de la apreciación teórica de los autores sobre su diagnóstico, orientación, educación, prevención, tratamiento y rehabilitación. Métodos: se realizó una revisión bibliográfica sobre la dependencia emocional por las bases de datos SciELO y Google Académico con predominio de los últimos 5 años, con la mirada multicausal, multidisciplinar, eminentemente psicológica, integracionista de la psicología cubana y de la escuela histórico-cultural de Vygotsky, consecuentes con lo psicobiológico, socio-económico-cultural en interacción con lo cualitativo-cuantitativo y lo clínico-epidemiológico. Desarrollo: se referenciaron múltiples disciplinas de las ciencias humanísticas, con el liderazgo de la psicología y el axioma vigotskiano: "...más allá de las potencialidades humanas para adaptarse al medio, están las posibilidades transformadoras del ser humano"; se reconocieron herramientas instrumentadas, devenidas en procesos psicológicos, protectores de personas con dependencia emocional. Conclusiones: la prevención de la dependencia emocional y su control, valorada a través de la escuela vigotskiana se apoya en la estimulación de la zona de desarrollo próximo y en la explicación de la situación social del desarrollo, regulada por actividades socio-culturales con su base natural en el sistema nervioso, regida por órganos funcionales, sin trasmisión biológica, con implicaciones de la psiconeuroinmunología, a partir de la cual se trata de solucionar el dilema cuerpo-mente relacionado con el tema.

ABSTRACT Introduction: the ideas of L.S. Vygotsky (1896-1934) theorist of the historical-cultural approach with his proposal to elaborate a materialist-dialectic psychological theory and practice are considered. Objective: to assess emotional dependence with its causes and associated factors based on the theoretical appreciation of the authors about its diagnosis, orientation, education, prevention, treatment and rehabilitation. Methods: a bibliographic review on emotional dependence was carried out by the SciELO and Google scholar databases with a predominance of the last 5 years, with a multicausal, multidisciplinary, eminently psychological, integrationist view of Cuban psychology and the historical-cultural school of Vygotsky, consistent with the psychobiological, socio-economic-cultural in interaction with the qualitative-quantitative and the clinical-epidemiological. Development: multiple disciplines of the humanistic sciences were referenced, with the leadership of psychology and the Vigotskian axiom: "... beyond the human potentialities to adapt to the environment, there are the transforming possibilities of the human being"; Instrumented tools were recognized, turned into psychological processes, protectors of people with emotional dependence. Conclusions: the prevention of emotional dependence and its control is valued through the Vigotskian school which is based on the stimulation of the zone of proximal development and on the explanation of the social situation of development, regulated by socio-cultural activities with its natural base in the nervous system, that is governed by functional organs, without biological transmission, with implications of psychoneuroimmunology, from which it is a matter of solving the mind-body dilemma related to the subject.

Assessment of captive rearing conditions on loggerhead hatchlings: Effect of handling frequency and stocking density.

Frequently, stranded sea turtles require rehabilitation under controlled conditions. Currently, few publications have described the conditions under which rehabilitation is to take place, particularly with respect to the hatchling life stage. To address this paucity of data, we conducted some experiments to assist rehabilitating facilities assess their handling of hatchlings. While in captivity, hatchlings are routinely handled, for example, for data collection and cleaning. Standardization of handling and housing protocols is necessary to define the most adequate rearing conditions to maintain hatchling welfare. Accordingly, the aim of this study was to assess plasma circulating corticosterone (Cort) concentration and growth, as a biomarker for the stress of hatchling loggerhead sea turtles (Caretta caretta) under controlled conditions. We performed two experiments to analyze handling frequency and stocking density. In both, Cort was measured and correlated with variations in animal weight and length. In handling experiments, Cort exhibited no significant increase when hatchlings were handled once a week, whereas Cort was significantly elevated when hatchlings were handled once every 2 weeks, suggesting that hatchlings have the ability to acclimate to frequent handling. However, hatchlings exhibited similar growth and mortality, regardless of handling regime. In stocking density experiments, hatchling isolation induced a significant elevation of Cort, in comparison with hatchlings placed with conspecifics at increasing densities. Growth increased in singly housed hatchlings, while mortality increased in tanks with three or more hatchlings. The results obtained suggest that Cort, growth, and mortality should be measured to assess hatchling welfare when kept under controlled conditions.

High levels of infant handling by adult males in Rwenzori Angolan colobus (Colobus angolensis ruwenzorii) compared to two closely related species, C. guereza and C. vellerosus.

Infant handling (holding or carrying) by adult males is rare in mammals; however, high levels have been reported in some primates. Though infant handling is a costly behaviour, there are many benefits that male handlers can accrue. Infant handling by males is most conspicuous in platyrrhines and tends to be uncommon in catarrhines. In the latter species, research on male-infant interactions has focused on low-cost behaviours, such as proximity and grooming. However, to better understand the evolution of infant handling by males, more data on its occurrence across the Primate order are essential, even in species where it is relatively uncommon. We compare the occurrence of infant handling by males in three closely related species of catarrhine: Colobus vellerosus, C. guereza, and C. angolensis ruwenzorii. We collected focal animal samples on infants to quantify infant handling rates and durations, and found that adult male C. a. ruwenzorii handled infants much more frequently and for much longer than males in the other two species. We discuss how C. a. ruwenzorii's unique social organization may explain high levels of infant handling by adult males in this species. More long-term and detailed comparisons of infant handling across species and populations will shed light on how sociality has shaped the evolution of this behaviour in the Primate order.

BLOOD LACTATE CONCENTRATIONS IN EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA) FOLLOWING CAPTURE BY A CANINE SEARCH TEAM.

Studies to assess wildlife health commonly evaluate clinical pathology changes, immune responses, pathogen presence, and contaminant exposure, but novel modalities are needed to characterize the unique physiologic responses of reptiles. Lactate is an indicator of hypoperfusion and/or anaerobic respiration and can be quickly and easily measured using a point-of-care analyzer. This study evaluated baseline blood lactate concentrations in free-living eastern box turtles (Terrapene carolina carolina, n = 116) using a point of care analyzer and then determined the effect of handling time, physical examination (PE) abnormalities, and quantitative polymerase chain reaction pathogen detection (Terrapene herpesvirus 1, Mycoplasma sp., Terrapene adenovirus) on lactate concentrations. Blood lactate concentrations were higher in turtles with Terrapene herpesvirus 1 (n = 11), quiet mentation, and increased packed cell volume (P < 0.05). Lactate concentrations increased between initial capture and PE, with peak values reaching 129 min after capture. Lactate at PE was positively associated with baseline lactate concentrations. Turtles with Terrapene herpesvirus 1 may have alterations in blood flow, oxygen delivery, or activity patterns, driving increases in baseline lactate. Increased handling time likely leads to more escape behaviors and/or breath holding, causing turtles to undergo anaerobic metabolism and raising lactate concentrations. Overall, lactate measured by a point of care analyzer shows variability caused by capture and health factors in eastern box turtles and may be a useful adjunctive diagnostic test in this species after full methodologic validation.

Increased MMP-9 levels with strain-dependent stress resilience and tunnel handling in mice.

Increased perineuronal net (PNN) deposition has been observed in association with corticosteroid administration and stress in rodent models of depression. PNNs are a specialized form of extracellular matrix (ECM) that may enhance GABA-mediated inhibitory neurotransmission to potentially restrict the excitation and plasticity of pyramidal glutamatergic neurons. In contrast, antidepressant administration increases levels of the PNN-degrading enzyme matrix metalloproteinase-9 (MMP-9), which enhances glutamatergic plasticity and neurotransmission. In the present study, we compare pro-MMP-9 levels and measures of stress in females from two mouse strains, C57BL/6 J and BALB/cJ, in the presence or absence of tail grasping versus tunnel-associated cage transfers. Prior work suggests that C57BL/6 J mice show relatively enhanced neuroplasticity and stress resilience, while BALB/c mice demonstrate enhanced susceptibility to adverse effects of stress. Herein we observe that as compared to the C57BL/6 J strain, BALB/c mice demonstrate a higher level of baseline anxiety as determined by elevated plus maze (EPM) testing. Moreover, as determined by open field testing, anxiety is differentially reduced in BALB/c mice by a choice-driven tunnel-entry cage transfer technique. Additionally, as compared to tail-handled C57BL/6 J mice, tail-handled BALB/c mice have reduced brain levels of pro-MMP-9 and increased levels of its endogenous inhibitor, tissue inhibitor of metalloproteinase-1 (TIMP-1); however, tunnel-associated cage transfer increases pro-MMP-9 levels in BALB/c mice. BALB/c mice also show increases in Western blot immunoreactive bands for brevican, a constituent of PNNs. Together, these data support the possibility that MMP-9, an effector of PNN remodeling, contributes to the phenotype of strain and handling-associated differences in behavior.

Simultaneous antagonism of dopamine D1/D2/D3 receptor in the NAc reduces 50-kHz ultrasonic calls in response to rhythmic tactile stroking.

Tactile stimulation such as rhythmic stroking elicits 50-kHz ultrasonic vocalizations (USVs) in rats that are thought to reflect positive affective states. Dopaminergic neurotransmission in the nucleus accumbens (NAc) is required for tactile reward-induced 50-kHz USVs; however, it is still unknown whether the accumbal dopaminergic system differentially modulates 50-kHz USV call subtypes induced by rhythmic stroking. We therefore examined both total and categorized 50-kHz USV rate, peak frequency, and duration under dopamine (DA) receptor antagonism in the NAc shell. Bilateral injection of the D1 receptor antagonist SCH 23390 (500 ng/side) plus the D2/D3 receptor antagonist raclopride (25 µg/side) significantly reduced the number of predominantly flat calls with harmonics during stimulation and the number of frequency-modulated (FM) calls after stimulation. In contrast, there were no substantial changes in total and categorized 50-kHz USVs mean peak frequencies and call durations. Therefore, emission of different subtypes of 50-kHz USVs may be differently regulated by dopaminergic transmission. The 50-kHz harmonics and FM USVs induced by rhythmic stroking may be useful behavioral markers for tactile reward in rats.

Neurodevelopmental testing of mice in the neonatal period does not affect their locomotor activity, depressive- and anxiety-like behaviour in adolescence.

Neonatal life is a sensitive period of brain plasticity. There are concerns that pre-weaning handling may therefore alter behavioural phenotype in adolescence or adulthood. Since neurodevelopment tests require daily manipulation with pups, later behavioural outcomes might be biased by repeated handling during suckling period. The aim of our study was to assess whether daily neurodevelopmental testing would cause alterations in behavioural phenotype. Sixty-four CD1 mice were randomized to tested and not tested group. In the tested group, maturation of physical features and neurodevelopment were monitored daily from postnatal day 1-21 between 9 and 11 AM. After weaning, battery of behavioural tests to monitor anxiety-like, depressive, or repetitive behaviour was performed in all mice. We revealed no significant between-group differences in performance of these tests. Our data did not confirm the assumption that early neurodevelopment testing during suckling period affects behavioural phenotype in adolescence.

Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia.

Handling of laboratory mice affects animal wellbeing and behavioural test outcomes. However, present research has focused on handling effects in common strains of laboratory mice despite the knowledge that environmental factors can modify established phenotypes of genetic mouse models. Thus, we examined the impact of handling on the face validity of a transgenic mouse model for the schizophrenia risk gene neuregulin 1 (i.e. Nrg1 type III overexpression). Nrg1 III tg and wild type-like (WT) control mice of both sexes underwent tail or tunnel handling before being assessed in the open field (OF), elevated plus maze (EPM), social preference/novelty, prepulse inhibition, and fear conditioning tests. Tunnel-handling reduced the startle response in all mice, increased OF locomotion and exploration in males and reduced anxiety in males (OF) and females (EPM) compared to tail-handling. Importantly, tunnel handling induced a more pronounced startle response to increasing startle stimuli in Nrg1 III tg females compared to respective controls, a phenomenon absent in tail-handled females. Finally, Nrg1 III tg males displayed reduced OF exploration and centre locomotion and Nrg1 III tg females displayed increased cue freezing over time compared to controls. In conclusion, handling methods have a significant impact on a variety of behavioural domains thus the impact of routine handling procedures need be considered when testing behavioural phenotypes. Handling did not change the main schizophrenia-relevant characteristics of Nrg1 III tg mice but affected the acoustic startle-response in a genotype- and sex-specific manner. Future research should evaluate the effect of handling on other genetic models.

Regular touchscreen training affects faecal corticosterone metabolites and anxiety-like behaviour in mice.

Automated touchscreen techniques find increasing application for the assessment of cognitive function in rodents. However, hardly anything is known about the potential impact of touchscreen-based training and testing procedures on the animals under investigation. Addressing this question appears particularly important in light of the long and intensive training phases required for most of the operant tasks. Against this background, we here investigated the influence of regular touchscreen training on hormones and behaviour of mice. Faecal corticosterone metabolites (FCMs), reflecting corticosterone levels around the time of treatment, were significantly increased in touchscreen-trained mice, even one week after the training phase was already terminated. Such an effect was not detected on baseline FCMs. Thus, regular touchscreen training can be assumed to cause long-term effects on hypothalamus-pituitary-adrenal axis activity. Furthermore, anxiety-like behaviour was increased in touchscreen-trained mice two weeks after the end of the training phase. Traditionally, this would be interpreted as a negative influence of the training procedure on the animals' affective state. Yet, we also provide two alternative explanations, taking the possibility into account that touchscreen training might have enriching properties.

Behaviour Management of the Contemporary Child in Paediatric Dentistry: An Overview of the Research

ABSTRACT Objective: To provide an overview of the most relevant studies on non-pharmacological behaviour management techniques for contemporary children, the so-called alpha generation, who undergo dental treatment. Material and Methods: A systematic search was performed on the Medline/PubMed and Google Scholar (grey literature) databases. The articles were read and data collected by two reviewers on an independent basis. Two reviewers collected data from the studies selected in tables structured by using the Rayyan QCRI software. The following data were extracted: year of study, child's age, child's gender, technique used. Results: A total of 322 articles were found, remaining only 17 after duplicates were removed and inclusion and exclusion criteria applied. The studies were conducted between 2010 and 2019 in Saudi Arabia, Greece, India, Brazil, USA, Italy, and Switzerland. The samples ranged from 15 to 306 children aged between 3 and 10 years old. The children attended the dental office for different reasons, ranging from simple prevention to endodontic treatment under local anaesthesia. Several behaviour modification methods are known to be used before and during a dental consultation. Conclusion: After reading the articles, we concluded that alpha generation children are inserted in a daily environment of modernization and that conventional non-pharmacological techniques using technology, such as audio-visual glasses, are more interesting and make children distracted and relaxed during dental treatment, thus minimizing their stress, anxiety and fear.